
11 - 50 employees
Founded 2024
🤖 Artificial Intelligence
🔬 Science
☁️ SaaS
Artificial Intelligence • Science • SaaS
FirstPrinciples is a research company building AI systems for discovery in fundamental science. It develops domain-specialized models and tools (branded Theo: Theo Collaborator, Theo Conjecture, and Theo, the AI Physicist) to assist the scientific process—hypothesis generation, symbolic reasoning, tool integration, validation loops, and reproducible research objects. The company emphasizes transparency, stewardship of knowledge as a public good, and alignment with the scientific community. Technical claims include multiple fine-tuned models across physics domains, a model family with 120B+ parameters trained on a curated corpus of 3M+ scientific papers, and internal experiments in areas like quantum information.
🕒 August 21
Where this job comes from
Posted on FirstPrinciples's careers page, not through a job board
First seen by Remote Rocketship August 21

11 - 50 employees
Founded 2024
🤖 Artificial Intelligence
🔬 Science
☁️ SaaS
Artificial Intelligence • Science • SaaS
FirstPrinciples is a research company building AI systems for discovery in fundamental science. It develops domain-specialized models and tools (branded Theo: Theo Collaborator, Theo Conjecture, and Theo, the AI Physicist) to assist the scientific process—hypothesis generation, symbolic reasoning, tool integration, validation loops, and reproducible research objects. The company emphasizes transparency, stewardship of knowledge as a public good, and alignment with the scientific community. Technical claims include multiple fine-tuned models across physics domains, a model family with 120B+ parameters trained on a curated corpus of 3M+ scientific papers, and internal experiments in areas like quantum information.
• Develop fluency in customers’ technical domains, research programs, and scientific problems to identify where FirstPrinciples can create value • Prepare targeted account strategies and outreach based on understanding of each organization and its work • Build relationships and pipeline across commercial R&D teams, industry researchers, research groups, national laboratories, and other research-intensive organizations • Own the end-to-end commercial lifecycle from prospecting and qualification through discovery, demos, proposals, and close • Run technically credible discovery conversations and product demos connecting researchers’ goals to concrete product use cases • Help prospective customers structure pilot plans, establish success criteria, and build confidence in platform adoption • Navigate scientific, technical, administrative, procurement, and leadership stakeholders • Partner with Research Partners through discovery, evaluation, onboarding, and expansion • Bring market feedback, objections, and emerging use cases to product, research, and engineering teams • Build scalable systems for outreach, qualification, account planning, CRM management, follow-up, and forecasting • Own pipeline, conversion, and revenue goals while helping define the early sales playbook
• Exceptionally curious and analytical, with the ability to rapidly develop fluency in unfamiliar technical and scientific domains • High agency and learning velocity; comfortable operating without an established playbook • Ability to form strong, testable points of view from incomplete information using first-principles reasoning • Commercial mindset and interest in turning complex technology into customer relationships, adoption, and revenue • Strong communication skills, including sharp questioning, careful listening, credible discovery conversations, and advancing opportunities toward decisions • Comfortable initiating conversations, prospecting into new organizations, and building relationships from the ground up • Persistent and highly organized, with accountability for measurable commercial outcomes • Background may include sales, investing, consulting, banking, data/analytics, a technical startup, scientific commercialization, or another highly analytical environment • Traditional enterprise sales experience is not required
• Remote-first work with flexibility in how you structure your day • High-trust, low-bureaucracy environment with real ownership • Exposure to cutting-edge ideas across AI, scientific discovery, and emerging technologies • Opportunity to work on foundational problems at the intersection of AI and physics • Culture that values curiosity, depth of thinking, and first-principles reasoning • Chance to contribute to work aimed at advancing fundamental science
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