Associate Director – Health Economics and Outcomes Research, Early Stage Pipeline

🕒 March 27

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Logo of Ionis Pharmaceuticals, Inc.

Ionis Pharmaceuticals, Inc.

501 - 1000 employees

Founded 1989

🧬 Biotechnology

💊 Pharmaceuticals

Biotechnology • Pharmaceuticals

Ionis Pharmaceuticals, Inc. is a biopharmaceutical company focused on discovering and developing RNA- and DNA-targeted medicines to treat serious diseases. The company leverages oligonucleotide chemistry and genetic insights to advance a pipeline of therapeutics across neurology, cardiometabolic disorders, and other high-need areas, conducting clinical trials and commercial collaborations to deliver medicines to patients. Ionis emphasizes scientific innovation, patient advocacy, and corporate responsibility in its efforts to translate genetic science into transformative therapies.

📋 Description

• The Associate Director/ Director of Health Economics and Outcomes Research (Early Stage Pipeline) will be responsible for defining and executing early evidence generation strategies and deliverables across multiple programs. • Support HEOR/COA endpoint strategy from Phase 1 to 3 clinical studies ensuring inclusion of patient-centric, clinically meaningful, and economically relevant outcomes. • Contribute to commercial and global market access strategy to influence trial designs that meet expectations from multiple stakeholders. • Lead development of HTA-grade cost-effectiveness and budget-impact models to support early decision-making, identify value drivers, pricing, value dossiers, and individual country-specific submissions. • Build relationships with clinical and HEOR/HTA thought leaders and academic collaborators shaping input to specific projects and methodologies, particularly in rare disease; contribute to business development activities and support existing Ionis business partnerships.

🎯 Requirements

• Advanced degree(s) (MD, PhD, PharmD, MSc, MPH, or equivalent) in Health Economics, Outcomes Research, Economics, Health Services Research, Business or psychometrics. • Associate Director: 8+ years and a master’s degree; or a PhD with 5+ years’ experience in pharmaceutical, biotechnology, or HEOR consulting environments; rare disease or neurology/cardiometabolic experience preferred. • Director: 12+ years and a master’s degree; or a PhD with 8+ years’ experience in pharmaceutical, biotechnology, or HEOR consulting environments; rare disease or neurology/cardiometabolic experience preferred. • Excellent communicator with proven interpersonal skills and ability to influence R&D, Commercial, Medical, and Regulatory teams. • Strong scientific writing and oral presentation skills. • Travel expectation is 30%

🏖️ Benefits

• Highly competitive benefits

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