Associate Director, Computational Development

🕒 April 6

🏄 California – Remote

🏄 California – Remote

💵 $192k - $208k / year

⏰ Full Time

🟠 Senior

👔 Director

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Veracyte, Inc.

WebsiteLinkedInAll Job Openings

501 - 1000 employees

Founded 2013

🧬 Biotechnology

⚕️ Healthcare Insurance

💊 Pharmaceuticals

Biotechnology • Healthcare Insurance • Pharmaceuticals

Veracyte, Inc. is a genomic diagnostics company focused on empowering clinicians with high-value molecular tests for diagnosing and treating cancer. The company provides a portfolio of genomic classifiers for various types of cancer, including thyroid, prostate, lung, breast, and bladder cancer, as well as interstitial lung disease. Veracyte's tests help clinicians and patients make informed decisions about cancer care by providing clear diagnostic and prognostic insights. The company's approach involves identifying unmet clinical needs and developing high-performance tests that are widely accessible globally through a CLIA and in vitro diagnostic-based model. Committed to elevating the standard of cancer care, Veracyte continues to expand its test portfolio and make significant contributions to the field of oncology diagnostics.

📋 Description

• Provide bioinformatics leadership for MRD assay design, development, and optimization across one or more LDT programs, ensuring alignment with scientific, clinical, and business objectives. • Serve as a senior scientific contributor and reviewer for assay concepts, signal detection strategies, error suppression approaches, and MRD calling methodologies. • Apply deep expertise in cancer genomics, ctDNA biology, and NGS technologies to guide assay architecture and analytical decision‑making. • Lead and/or oversee analytical study design and data analysis for assay development and validation, including accuracy, limit of detection, precision, and robustness. • Guide development, validation, and maintenance of scalable, production‑ready bioinformatics pipelines supporting MRD analysis, QC, and reporting. • Review and approve analytical approaches, benchmarking studies, and optimization strategies, ensuring scientific rigor and regulatory readiness. • Ensure compliance with standards (CAP/CLIA, FDA, IVDR) throughout the bioinformatics development lifecycle, including rigorous testing and documentation. • Provide day‑to‑day scientific mentorship and technical guidance to bioinformatics scientists and senior scientists. • Support career development of team members through coaching, technical review, and knowledge sharing. • Communicate complex analytical concepts clearly to stakeholders at varying levels of technical depth, including senior leadership.

🎯 Requirements

• Ph.D. in Bioinformatics, Computational Biology, Genomics, Biostatistics, or a closely related quantitative field. • Minimum 8 years of total relevant experience, with at least 5 years of management experience in biotech, diagnostics, or regulated healthcare environments. • Demonstrated experience leading NGS‑based assay development for clinical diagnostics. Hands‑on experience with ctDNA‑based MRD assays, including personalized or tumor‑informed approaches. • Strong programming skills in Python, with experience developing and benchmarking reproducible, production‑grade analysis pipelines, including experience with SDLC best practices. • Proven experience working in design‑controlled, regulated environments (CAP/CLIA LDT, IVD, or equivalent) is a must. • Track record of working with wet lab scientists on iterative experiment design, execution, analysis, and interpretation as a tightly integrated team. • Demonstrated record of technical and scientific leadership, ownership, and independent work.

🏖️ Benefits

• Health insurance • Competitive compensation • Professional development opportunities • Flexible work arrangements • Inclusion in a diverse workforce