VP, Global In Vitro – Scientific Operations

🕒 June 30

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Logo of Crown Bioscience

Crown Bioscience

1001 - 5000 employees

🧬 Biotechnology

💊 Pharmaceuticals

🏥 Healthcare

💰 $26.6M Series D - Crown Bioscience on 2014-05

Biotechnology • Pharmaceuticals • Healthcare

Crown Bioscience is a Contract Research Organization (CRO) specializing in translational oncology and immuno-oncology drug discovery and development. The company provides integrated preclinical and translational services — including extensive patient-derived systems (PDX models, organoids), cell line and CDX panels, engineered and humanized in vivo models, DMPK/toxicology, biomarker discovery and clinical biomarker services, digital pathology and high-content imaging, and bioinformatics/data solutions — to help biotech and pharmaceutical clients advance oncology therapeutics. Crown supports next-generation therapeutic modalities (ADCs, cell & gene therapies, radiopharmaceuticals), focuses on cancer indications such as AML, breast, prostate and pancreatic cancers, and maintains large model/databases and partnerships to enable model selection, target validation, and translational biomarker development.

📋 Description

• Lead all global in vitro scientific operations across Crown’s sites. • Ensure consistent and high-quality execution of in vitro studies, maintaining strong scientific rigor, reproducibility, and translational relevance. • Drive operational efficiencies through standardized workflows, SOP harmonization, and continuous improvement initiatives. • Oversee end-to-end operational workflows, including study design support, resource planning, execution, QC, reporting, and on-time delivery. • Drive improvements in productivity, reproducibility, cycle time, and cross-site alignment. • Establish and track operational KPIs (quality, timeliness, resource utilization, client satisfaction). • Identify opportunities to expand and modernize in vitro capabilities. • Lead implementation of new technologies, automation, and translational assays supporting MoA, PK/PD linkage, and IND-enabling studies. • Act as a senior scientific representative for key client meetings, supporting proposal development, study design, troubleshooting, and data interpretation. • Support BD strategy with strong scientific storytelling, customer retention insights, and expansion of strategic partnerships. • Guide teams in translating client program objectives into actionable in vitro study plans. • Ensure alignment between scientific operations, project management, quality, and commercial teams. • Build a high-performance culture emphasizing scientific rigor, innovation, accountability, and client-centricity.

🎯 Requirements

• Ph.D. in cancer biology, immunology, pharmacology, molecular/cell biology, or related discipline. • 10+ years of experience in oncology/immunology preclinical research with deep expertise in in vitro assay platforms. • 7+ years of leadership experience managing scientific teams, ideally across multiple global sites. • Demonstrated track record in CRO scientific operations, with strong understanding of client expectations and data delivery requirements. • Extensive experience designing, executing, and interpreting mechanistic in vitro assays, immune effector studies, co-culture systems, and imaging-based platforms. • Proven ability to manage operational workflows, introduce new capabilities, and ensure high-quality scientific output. • Excellent communication skills, with experience in client-facing scientific roles.

🏖️ Benefits

• Health insurance • Retirement plans • Flexible work arrangements • Professional development

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