Principal Software Engineer

🕒 May 29

🍂 Massachusetts – Remote

🍂 Massachusetts – Remote

💵 $152k - $190k / year

⏰ Full Time

🔴 Lead

🧑‍💻 Full-stack Engineer

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eClinical Solutions

WebsiteLinkedInAll Job Openings

201 - 500 employees

Founded 2012

🧬 Biotechnology

💊 Pharmaceuticals

⚕️ Healthcare Insurance

💰 Private Equity Round on 2020-01

Biotechnology • Pharmaceuticals • Healthcare Insurance

eClinical Solutions is a clinical data management company that provides integrated data review and management solutions for the biotech and pharmaceutical industries. Their platform, elluminate, empowers organizations to modernize and automate their clinical data workflows, ensuring efficient data acquisition, management, and analysis. By leveraging advanced analytics and technology-driven approaches, eClinical Solutions helps streamline trial operations and improve productivity, enabling better decision-making in clinical research.

📋 Description

• Design, develop, test, and deploy scalable, secure, and highly interactive web applications • Own and evolve core platform modules, from concept through release and support • Influence application and system architecture with a focus on performance, reliability, security, and maintainability • Lead by example through clean, well-tested code, thoughtful design reviews, and pragmatic technical decisions • Collaborate closely with Product Management, QA, and other engineers throughout the SDLC • Provide technical mentorship and guidance to other engineers on the team • Diagnose and resolve complex production issues across distributed systems • Ensure solutions meet eClinical Solutions quality standards and applicable industry regulations • Contribute to technical documentation including design specs, acceptance criteria, and release notes.

🎯 Requirements

• Bachelor’s or Master’s degree in Computer Science or equivalent practical experience • 10+ years in software design and development using the Microsoft technology stack preferred • Expert-level proficiency in C#, .NET, and ASP.NET (MVC/Web APIs) • Strong experience building full-stack web applications (Angular, TypeScript, HTML, CSS) • Solid understanding of software design principles, patterns, and best practices • Experience across the full Software Development Lifecycle (Agile preferred) • Proven ability to work independently while collaborating effectively in a fast-paced environment • Excellent communication, documentation, and technical leadership skills. • Hands-on experience integrating LLM-based services (e.g., OpenAI, Azure OpenAI, or similar) into applications • Experience using Python and/or .NET alongside AI/LLM workflows • Familiarity with agent-based or workflow-driven AI architectures is a strong plus • Understanding of secure and responsible AI usage in enterprise systems. • Strong SQL expertise (Microsoft SQL Server preferred), including performance tuning • Experience with microservices, distributed systems, and cloud platforms (AWS preferred) • Secure development experience, including awareness of common vulnerabilities and mitigations • Experience with clinical trial data, life sciences, or regulated SaaS environments • Experience building data visualizations or analytics-driven user experiences.

🏖️ Benefits

• Health insurance • Retirement plans • Paid time off • Flexible work arrangements • Professional development