Principal Software Engineer

🕒 August 6

🍂 Massachusetts – Remote

🍂 Massachusetts – Remote

💵 $152k - $190k / year

⏰ Full Time

🔴 Lead

🧑‍💻 Full-stack Engineer

🦅 H1B Visa Sponsor

This company has sponsored H1B visas in the past.

👻 Ghost score 0%

What it means: how likely this posting is sitting open without active hiring.How to read it: 60% or higher means we think this is a ghost. Lower scores are less of a worry.How we score it: age, reposts, open roles vs team size, how fast jobs close, and whether pay is listed.Fine print: an estimate from public data, not a judgment of the company. Real jobs can score high, so treat it as a hint, not a fact.

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eClinical Solutions

WebsiteLinkedInAll Job Openings

201 - 500 employees

Founded 2012

💼 Consulting

🏥 Healthcare

🧬 Biotechnology

💰 Private Equity Round on 2020-01

Consulting • Healthcare • Biotechnology

eClinical Solutions is a clinical data management company that provides integrated data review and management solutions for the biotech and pharmaceutical industries. Their platform, elluminate, empowers organizations to modernize and automate their clinical data workflows, ensuring efficient data acquisition, management, and analysis. By leveraging advanced analytics and technology-driven approaches, eClinical Solutions helps streamline trial operations and improve productivity, enabling better decision-making in clinical research.

📋 Description

• Design, develop, test, and deploy scalable, secure, and highly interactive web applications • Own and evolve core platform modules from concept through release and support • Influence application and system architecture, focusing on performance, reliability, security, and maintainability • Lead by example through clean, well-tested code, design reviews, and pragmatic technical decisions • Collaborate with Product Management, QA, and engineers throughout the SDLC • Provide technical mentorship and guidance to engineers • Diagnose and resolve complex production issues across distributed systems • Ensure solutions meet eClinical Solutions quality standards and applicable industry regulations • Contribute to technical documentation, including design specs, acceptance criteria, and release notes • Integrate LLMs and AI services into .NET- and Python-based systems • Design and implement AI-assisted workflows, copilots, and intelligent automation features • Work with agentic AI patterns such as task orchestration, tool-using agents, and workflow automation • Apply prompt engineering, evaluation techniques, and guardrails for reliability and compliance • Collaborate with data and platform teams to operationalize AI in production products

🎯 Requirements

• Bachelor’s or Master’s degree in Computer Science or equivalent practical experience • 10+ years in software design and development using the Microsoft technology stack preferred • Expert-level proficiency in C#, .NET, and ASP.NET (MVC/Web APIs) • Strong experience building full-stack web applications with Angular, TypeScript, HTML, and CSS • Solid understanding of software design principles, patterns, and best practices • Experience across the full Software Development Lifecycle; Agile preferred • Ability to work independently and collaborate effectively in a fast-paced environment • Excellent communication, documentation, and technical leadership skills • Hands-on experience integrating LLM-based services such as OpenAI or Azure OpenAI into applications • Experience using Python and/or .NET alongside AI/LLM workflows • Familiarity with agent-based or workflow-driven AI architectures is a strong plus • Understanding of secure and responsible AI usage in enterprise systems • Strong SQL expertise, including performance tuning, is a nice to have • Experience with microservices, distributed systems, and cloud platforms such as AWS is a nice to have • Secure development experience, including awareness of common vulnerabilities and mitigations, is a nice to have • Experience with clinical trial data, life sciences, or regulated SaaS environments is a nice to have • Experience building data visualizations or analytics-driven user experiences is a nice to have

🏖️ Benefits

• Remote work • Work-life balance • Inclusive culture • Opportunities to learn, grow, and continuously improve • Equal opportunity employment